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Also known as Jatzkewitz-Pilz syndrome, GM2 Gangliosidosis, and Beta-hexosaminidase-beta-subunit deficiency. Sandhoff disease is a rare, inherited, lipid storage disorder that progressively destroys neurons in the brain and spinal cord. This autosomal recessive disease is caused by a deficiency of enzyme beta-hexosaminidase A and B, which leads to a build-up of GM2 gangliosides in tissues. Juvenile and adult forms are more rare than infantile. Due to the nearly total absence of hexosaminida.
Sandhoff Disease in Arizona, USA. Thursday, June 5, 2008. My goal with this blog site is to increase awareness about the occurrences of Sandhoff Disease in Arizona and throughout the United States. Through raising awareness, I believe the right people will get involved to continue the fight to find a cure as well as implement support systems for the ones suffering right now.
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Sandhole is Tehsil of the Mandi district of Himachal Pradesh. Earlier it was a sub tehsil of the Sarkhaghat tehsil and Dharampur development block. It was officially upgraded to tehsil on 30 June 2011 by then Chief Minister of State, Professor Prem Kumar Dhumal.